Archive: 2025/12 - Page 2
Tramadol and Serotonin Syndrome: Why This Opioid Is Different
Tramadol is an atypical opioid that can cause serotonin syndrome even alone - not just when mixed with antidepressants. Learn why it's riskier than morphine or oxycodone, who's most vulnerable, and what safer alternatives exist.
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How to Store Insulin and Biologics During Long Flights: A Practical Guide
Learn how to safely store insulin and biologics during long flights to prevent dangerous temperature damage. Essential tips for travelers with diabetes, including cooling wallets, TSA rules, and dosing adjustments for time zones.
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Complex Generic Formulations: Why Proving Bioequivalence Is So Hard
Complex generic formulations like inhalers, topical creams, and injectables are hard to copy because traditional bioequivalence tests don't work. Learn why proving they're as safe and effective as brand drugs is one of the biggest hurdles in generic medicine.
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Pharmacist Authority in Substitution: Legal Scope of Practice Across U.S. States
Pharmacists can legally substitute medications in most U.S. states, but rules vary widely. Learn how generic and therapeutic substitution work, which states allow what, and why this matters for patient access and healthcare costs.
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Sleep Medications and Sedatives in Seniors: Safer Sleep Strategies
Most sleep medications are unsafe for seniors, increasing fall and dementia risk. Learn safer alternatives like CBT-I and low-dose doxepin, and how to stop risky prescriptions.
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Litigation in Generic Markets: How Patent Disputes Delay Affordable Medicines
Patent disputes in the generic drug market delay affordable medicines, costing billions annually. Learn how the Hatch-Waxman Act, Orange Book listings, and serial litigation block competition-and what’s being done to fix it.
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Osteoporosis in Endocrine Disease: How FRAX and Bisphosphonates Guide Treatment
Osteoporosis in endocrine diseases like diabetes and thyroid disorders requires special attention. FRAX calculates fracture risk accurately, and bisphosphonates are the first-line treatment to prevent breaks. Here’s how to know if you need them.
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Pregnancy and Medications: What You Need to Know About Teratogenic Risks and Birth Defects
Learn which medications can cause birth defects during pregnancy, when risks are highest, and how to make safe choices. Get clear, evidence-based guidance on teratogens, acetaminophen, and what to do if you took medicine before knowing you were pregnant.
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Active vs Inactive Drug Ingredients: Why the Difference Matters for Your Health
Active ingredients treat your condition, but inactive ingredients make the pill work - and sometimes cause side effects. Learn why every component in your medication matters for your health and safety.
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Labeling Effect: How Calling a Drug 'Generic' Changes How Patients Feel and Respond
The labeling effect shows that calling a drug 'generic' can make patients feel it's less effective-even when it's chemically identical to the brand-name version. This psychological bias impacts adherence, side effects, and outcomes.
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